Application of 3-D Prismatic Optical Tracking to Single-Molecule Optical Tweezers
نویسندگان
چکیده
منابع مشابه
Single molecule mechanics of biopolymers: An optical tweezers study
Bibliography 97 Publications 101 Samenvatting (Dutch) 103 Dankwoord / Acknowledgments 107 iii Preface This work describes the project I have done in the Physics of Complex Systems group at the Vrije Universiteit, Amsterdam, to obtain my degree as Master of Physics. The project comprised micromechanical experiments on the semi-flexible biopolymers microtubules and F-actin. An independent measure...
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Forces hold everything together and determine its structure and dynamics. In particular, tiny forces of 1-100 piconewtons govern the structures and dynamics of biomacromolecules. These forces enable folding, assembly, conformational fluctuations, or directional movements of biomacromolecules over sub-nanometer to micron distances. Optical tweezers have become a revolutionary tool to probe the f...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2012
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2011.11.2100